More specifically, the comfort and guidance Christ offers his followers via the Holy Spirit is not reliant upon the System, which is evilly-motivated and wholly opposed to God and Creation.
How could it be otherwise?
We are all locked into the System to varying degrees. In this sense, none of us is truly free -- at least not in a worldly sense -- but this does not render the comfort and guidance of the Holy Spirit inaccessible.
Although we are locked into the System, we can still be spiritually free, mainly through repentance and thinking outwith the System.
When we repent our sins and learn to think beyond the System, we create the conditions needed to fully experience the comfort and guidance of the Holy Spirit.